• Welcome to DBEncRNA database

  • Bacterial non-coding RNA (ncRNA) is a class of gene expression regulators in bacteria in recent years. Similar to the concept of essential genes, a part of ncRNA is indispensable for the survival of organisms, which is called essential ncRNA. Therefore, the bacterial essential ncRNAs could be used as potential targets for drug development in order to reduce drug resistance in pathogenic bacteria.

  • The essential ncRNA has become one of the important objects of minimal genome research. At present, more than a dozen bacteria have been systematically identified their essential ncRNAs by experimental method. However, there is no specialized essential ncRNAs database. And hence, the research on essential ncRNAs is far behind the needs of scientific research and drug design.

    In consequence, in this study, a special Database of Bacterial Essential ncRNA (DBEncRNA) was proposed and constructed to help researchers develop the efficient recognition methods for essential ncRNA in silico, which further studies including antimicrobial target discovery and minimal genome research. The DBEncRNA database can be accessed by http://yeyn.group:86/ freely.
Organism RefSeq Condition No.f essential ncRNA
Caulobacter crescentus NC_011916 Rich medium 532
Acinetobacter baumannii ATCC 17978 NC_009085 Rich medium 60
Escherichia coli O157:H7 str. EDL933 NZ_CP008957 LB agar 37
Synechococcus elongatus PCC 7942 NC_007604 Rich Medium 34
Mycoplasma pneumoniae M129 NC_000912 LB agar 34
Sphingomonas wittichii RW1 NC_009511 Rich medium 32
Brevundimonas subvibrioides ATCC 15264 NC_014375 Rich medium 31
Mycobacterium tuberculosis H37Rv III NC_000962 Rich medium 29
Providencia stuartii strain BE2467 NZ_CP017054 LB medium 25
Salmonella enterica serovar Typhi Ty2 NC_016810 Rich medium 24
Salmonella enterica serovar Typhimurium SL1344 NC_016810 Rich medium 23
Streptococcus mutans UA159 AE014133 blood agar 6
Agrobacterium fabrum str. C58 chromosome linear NC_003063 Rich medium 6
Agrobacterium fabrum str. C58 chromosome circular NC_003062 Rich medium 5
Mycobacterium tuberculosis H42Rv III NC_000962 Rich medium 1
Mycobacterium tuberculosis H38Rv III NC_000962 Rich medium 1
Mycobacterium tuberculosis H39Rv III NC_000962 Rich medium 1
Mycobacterium tuberculosis H40Rv III NC_000962 Rich medium 1
Mycobacterium tuberculosis H41Rv III NC_000962 Rich medium 1
Mycobacterium tuberculosis H43Rv III NC_000962 Rich medium 1