DVSP

DVSP (The Database of Viruses Spike Protein) is a comprehensive database of spike protein/nucleotide from viruses. It contains extensive information about 35579 spike proteins and 35175 nucleotides extracted from protein and nucleotide sublibraries of NCBI.

DVSP is a database containing spike protein/nucleotide by Bioinformatics and Biomedical Big data Mining Laboratory in Guizhou Medical University. If you have any suggestion, please contact us by sending an e-mail to yyn@gmc.edu.cn.

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Spike protein is a class I virus fusion protein, which mediates the binding of the virus to the host cell receptor and the membrane fusion between the virus envelope and the host cell membrane during the virus invasion, thereby affecting the infection orientation of the cell. This is the first step necessary for entry into the host cell. S protein determines the host range and specificity of the virus, and is an important role site for neutralizing antibodies in the host, as well as a key target for vaccine design of related viruses.

We built DVSP to store not only sequence information but also text mining data. The spike protein data can be accurately matched based on the virus type, host source, corresponding Accession Number and nucleotide information. At the same time, the protein can also be retrieved based on the known limited information, such as description, accession number, sequence and other features. DVSP was designed to support data resources that can help facilitate research on immunotherapy, biologics and small molecule targeting, accurate prediction of gene epitopes to aid vaccine design, and basic research on spike-mediated virus structure recognition, function and pathogenesis.

Welcome to DVSP database